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李庆国
发布时间:2019-06-26      来源:药剂学学部       点击:


李庆国

学位:博士

职称:教授

药剂学学术型和中药学专业型硕士生导师。

教育、工作经历

2020/01-至今,新葡的京集团8814,新葡的京集团8814,教授

2010/01-2019/12,新葡的京集团8814,新葡的京集团8814,副教授

2015/05-2016/05,英国伯明翰大学,化学工程系,访问学者

2006/01-2009/12,新葡的京集团8814,新葡的京集团8814,讲师

2003/07- 2005/12  新葡的京集团8814,新葡的京集团8814,助教

2005/09- 2009/06,新葡的京集团8814,新葡的京集团8814 ,博士,导师:李卫民

2000/09-2003/06,湖北工业大学 ,生物工程与食品学院,硕士,导师:干信

1996/09-2000/06 ,湖北工业大学,生物工程与食品学院,学士

研究方向

从事制药工程、药学和中药学的教学和科研工作。科研方向为药物制剂新技术,主要利用喷雾干燥、热熔挤出、超临界流体和介质研磨等技术研究难溶性药物递送系统。主持广东省医学基金和广东省科技厅等多项基金,发表15篇SCI论文,授权4项发明专利。

承担的课程

主讲《化工原理》、《制药工程学》和《制药工程课程设计》等课程。获得新葡的京集团88142016-2017年“我心目中的好老师”。

代表性研究论文


[1] Qingguo Li, Deen Huang, Tiejun Lu, Jonathan P.K. Seville, Lei Xing, Gary A. Leeke*. Supercritical fluid coating of API on excipient enhances drug release. Chemical Engineering Journal. 2017, 313(4): 317-327. (IF: 13.273, top, Q1)

[2] Tingting Chen, Zhimin Ma, Zhenwen Qiu, hong Zhong, Lei Xing, Qiuping Guo, Dandong Luo, Zhiwei Weng, Fucheng Ge, Yating Huang, XiubingZhang, Hongling He, Xiaodong Zhuang*, Qingguo Li*, Tianhui Yuan*. Characterization of excipients to improve pharmaceutical properties of sirolimus in the supercritical anti-solvent fluidized process. International Journal of Pharmaceutics. 2022, 611:121240 (IF: 5.875, top, Q1)

[3] Chen Tingting, Liu Liuyi, Zhang Lei, Lu Tiejun, Matos Ravenna L, Jiang Cuiping, Lin Yisheng, Yuan Tianhui, Ma Zhimin, He Hongling, Zhuang Xiaodong*, Li Qingguo*. Optimization of the supercritical fluidized bed process for sirolimus coating and drug release. International Journal of Pharmaceutics. 2020, 589:119809 (IF: 5.875, top, Q1)

[4] Zhang Xiaoting, Rao Qiuhong, Qiu Zhenwen, Lin Yisheng, Zhang Lei, Hu Qingzhong, Chen Tingting, Ma himin, Gao Hanlu, Luo Dandong, Zhao Jiaqi, Ouyang Defang*, Zhang Zhenyu Jason*, Li, Qingguo*. Using acetone/water binary solvent to enhance the stability and bioavailability of spray dried enzalutamide/ HPMC-AS solid dispersions. Journal of Pharmaceutical Sciences. 2020,10 (IF: 2.993, Q2)

[5] Huang, Deen, Xie, Ziyuan, Rao, Qiuhong, Liamas, Evangelos, Pan, Piaopiao, Guan, SX*,; Zhang, Zhenyu ason, Lu, Ming*, Li, Qingguo*. Hot melt extrusion of heat-sensitive and high melting point drug: Inhibit the recrystallization of the prepared amorphous drug during extrusion to improve the bioavailability. International Journal of Pharmaceutics. 2019, 565: 316-324 (IF: 5.875, Q1)

[6] Leeke*.  Solubility of Azoxystrobin and Benflumetol in Compressed CO2-Measured by the Static Precise Mass Measuring Method. Journal of Chemical & Engineering Data. 2018.12. (IF: 2.196, Q2)

[7] Qingguo Li, Wenhai Huang, Juan Yang, Jianfeng Wang, Min Hu, Jianmei Mo, Yuzhu Cheng, Zhanlun Ou, Zhenyu Jason Zhang, Shixia Guan*, "Gastric retention pellets of edaravone with enhanced oral bioavailability: Absorption mechanism, development, and in vitro/in vivo evaluation", European Journal of Pharmaceutical Sciences, 119(2018):62-69. (IF: 3.466, Q2)

[8] Qiuhong Rao#, henwen Qiu#, Deen Huang, Tiejun Lu, Zhenyu Jason Zhang, Dandong Luo,Piaopiao Pan, Lei Zhang, Yingyan Liu, Shixia Guan*, Qingguo Li*. Enhancement of the apparent solubility and bioavailability of Tadalafil nanoparticles via antisolvent precipitation. European Journal of Pharmaceutical Sciences. 128 (2019) 222–231 (IF:3.466, Q2).

[9] Qingguo Li#, Jianmei Mo#, Wenru Wu, Juan Yang, Jinjin Li, Tianxing Lai, Zhanlun Ou, Zhenwen Qiu, Shixia Guan*, Junjie Liao*."Genetic diversity, population structure and identification of Dendrobium cultivars with high polysaccharide contents using SCoT, SCAR and nested PCR markers". Genetic resources and crop evolution. 2018, 10. (IF:1.13, Q2).

[10] Chengcheng Zhu, Haibo Yang, Liang Shen, Zhuoyuan Zheng, Shicheng Zhao,  Qingguo Li*, Fengbin Yu, Lian Cen*. Microfluidic preparation of PLGA microspheres as cell carriers with sustainable Rapa release.  Journal of Biomaterials Science, Polymer Edition. 2019, 30(9) :737–755.   (IF: 2.02, Q2)    

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