2017/9-至今 新葡的京集团8814 新葡的京集团8814(中医药数理工程研究院)     副研究员

2017/11-2015/11 中国中医科学院中药研究所/中山市中智药业集团有限公司 博士后 导师：陈士林、成金乐

2014/8-2015/11 中山市中智药业集团有限公司 技术人员

2009/9-2014/6  新葡的京集团8814 中药学 博士 导师：陈蔚文、林辉

2005/9-2009/6  新葡的京集团8814 制药工程(中药学)   学士

中药品质形成与评价

1）药用植物活性成分生物合成与调控；

2）中药分子鉴定

1. 横向企业合作项目，凉粉草种质资源收集及评价研究，2023.4－2025.3，19万，主持。

2. 国家自然科学基金委员会区域联合基金项目，岭南特色药用植物发育和品质形成的光温调控机制研究，2023.1.1－2026.12.31，257万，参与。

3. 广州市科技局科技计划项目，半夏产业关键技术研究与产业化示范，2022.4.1－2025.3.31，100万，参与。

4. 国家自然基金青年基金项目，81903741，龙脑樟中右旋龙脑生物合成关键酶基因BPPS的鉴定和功能研究，2020/1-2022/12，24万元，结题，主持；

5. 中国博士后科学基金面上项目，2016M602597，基于DGGE和HTS的中药破壁饮片混合物鉴定方法研究，2016/11-2017/10，结题，主持。

主要承担《分子生物学》、《本草基因组学》、《中药现代化关键技术》等课程。

[1] Chunzhu Xie, Ting Zhan, Jinqin Huang, Jun Laa, Lingling Shen, Hongbin Wang, Xiasheng Zheng. Functional characterization of nine critical genes encoding rate-limiting enzymes in the flavonoid biosynthesis of the medicinal herb Grona styracifolia. BMC Plant Biol 2023; 23: 299.

[2] Ting Zhan, Fuyu Li, Jun Lan, Linhuan Li, Zerui Yang, Chunzhu Xie, Hongbin Wang, Xiasheng Zheng. Functional characterization of four mono-terpene synthases (TPSs) provided insight into the biosynthesis of volatile monoterpenes in the medicinal herb Blumea balsamifera. Physiol Mol Biol Plants (2023).

[3] ZeruiYang,TingZhan,ChunzhuXie,SongHuang,XiashengZheng. Genome-wide analyzation and functional characterization on the TPS family provide insight into the biosynthesis of mono-terpenes in the camphor tree. Plant Physiology and Biochemistry. 2023 Mar; 196:55-64.

[4] 冯时茵,谢纯珠,蔡庆群,唐洪梅,郑夏生.广金钱草糖基转移酶基因GsUGT9的克隆和生物信息学分析[J].今日药学,2022,32(08):578-582.

[5] Yuying Huang, Jing Li, Zerui Yang, Wenli An, Chunzhu Xie, Shanshan Liu, Xiasheng Zheng. Comprehensive analysis of complete chloroplast genome and phylogenetic aspects of ten Ficus species. BMC Plant Biology, 2022, 23;22(1):253.

[6] Yuying Huang, Wenli An, Zerui Yang, Chunzhu Xie, Shanshan Liu, Ting Zhan, Huaigeng Pan, Xiasheng Zheng. Metabolic stimulation-elicited transcriptional responses and biosynthesis of acylated triterpenoids precursors in the medicinal plant Helicteres angustifolia, BMC Plant Biology, 2022, 25;22(1):86.

[7] Shanshan Liu, Shiyin Feng, Yuying Huang, Wenli An, Zerui Yang, Chunzhu Xie, Xiasheng Zheng, Characterization of the Complete Chloroplast Genome of Buddleja Lindleyana, Journal of AOAC INTERNATIONAL, 2021;, qsab066

[8] Chunzhu Xie , Wenli An, Shanshan Liu, Yuying Huang, Zerui Yang, Ji Lin, Xiasheng Zheng. Comparative Genomic Study on the Complete Plastomes of Four Officinal Ardisia Species in China. Sci Rep. 2021 Nov 15;11(1):22239.

[9] Zerui Yang, Chunzhu Xie, Ting Zhan, Linhuan Li, Shanshan Liu, Ying Yu Huang, Wenli An, Xiasheng Zheng, Song Huang.(2021)Genome-wide identification and functional characterization of the trans-prenyltransferase gene family in Cinnamomum camphora.Front. Plant Sci.

[10] Zerui Yang, Chunzhu Xie, Yuying Huang, Wenli An, Shanshan Liu, Song Huang, Xiasheng Zheng. Metabolism and transcriptome profiling provides Insight into the genes and transcription factors involved in monoterpene biosynthesis of borneol chemotype of Cinnamomum camphora induced by mechanical damage. PeerJ. 2021 Jul 1;9:e11465."

[11] Zheng, Xiasheng & An, Wenli & Yao, Hui & Xu, Jiang & Chen, Shilin. (2020). Rapid Authentication of the Poisonous Plant Gelsemium elegans by Combining Filter-Paper-Based DNA Extraction and RPA-LFD Detection. Engineering.

[12] Yansui Mai, Zerui Yang, Xiaoyu Ji, Wenli An, Yuying Huang, Shanshan Liu, Lian He, Xiaoping Lai, Song Huang & Xiasheng Zheng (2020) Comparative analysis of transcriptome and metabolome uncovers the metabolic differences between Dendrobium officinale protocorms and mature stems, All Life, 13:1, 346-359,

[13] Yang Z, An W, Liu S, Huang Y, Xie C, Huang S, Zheng X. Mining of candidate genes involved in the biosynthesis of dextrorotatory borneol in Cinnamomum burmannii by transcriptomic analysis on three chemotypes. PeerJ. 2020 Jun 10;8:e9311.

[14] An W, Li J, Yang Z, Huang Y, Huang S, Zheng X. Characteristics analysis of the complete Wurfbainia villosa chloroplast genome. Physiol Mol Biol Plants. 2020 Apr;26(4):747-758.

[15] Mai Y, Niu Z, He W, Lai X, Huang S, Zheng X. The Reparative Effect of Dendrobium officinale Protocorms against Photodamage Caused by UV-Irradiation in Hairless Mice. Biol Pharm Bull. 2019;42(5):728-735. doi: 10.1248/bpb.b18-00901. PMID: 31061314.

[16] Huang Y, Yang Z, Huang S, An W, Li J, Zheng X. Comprehensive Analysis of Rhodomyrtus tomentosa Chloroplast Genome. Plants (Basel). 2019 Apr 4;8(4):89. doi: 10.3390/plants8040089. PMID: 30987338; PMCID: PMC6524380.

[17] Zheng X, Ren C, Huang S, Li J, Zhao Y. Structure and features of the complete chloroplast genome of Melastoma dodecandrum. Physiol Mol Biol Plants. 2019 Jul;25(4):1043-1054. doi: 10.1007/s12298-019-00651-x. Epub 2019 Mar 12. PMID: 31404219; PMCID: PMC6656900.